Synchronization of the radiation plan with the current condition of the patient and the tumor can produce an optimal, personalized radiation result. We use our expertise in imaging, dosimetry and artificial intelligence for adaptive radiation therapy. We develop solutions for a safe and precise treatment that is effective and efficient. For example, we build mechatronic systems for precise (image-driven) positioning of the patient and radiation beam. We optimize the system design using simulations (FEM, multiphysics). In addition, we devote a lot of attention to improving the oncology workflow.